Professor Neeraj Saxena

Pain Expert

Professor Saxena

Professor Neeraj Saxena is an experienced consultant in pain medicine who provides expert evidence in civil proceedings

Instructing Professor Neeraj Saxena

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Profile

Professor Saxena’s clinical expertise lies in diagnosing painful conditions, prognosticating its course and planning its interdisciplinary management. He manages all chronic painful conditions, although the bulk of his work revolves around patients with musculoskeletal conditions (esp. low back pain/ spinal pain), post- traumatic pain, post-surgical pain, neuropathic pain (including complex regional pain syndrome) and fibromyalgia

Experience of giving evidence

Professor Saxena has trained extensively in medicolegal report writing and is accredited through Cardiff University-Bond Solon-civil experts.

He has been providing medicolegal services since 2017 and provides about 40 reports a year. He has attended Cardiff County Court to provide expert evidence.

His current split for claimant: defendant work is 7:1, with occasional joint instructions

Cases undertaken

  • Chronic pain
  • Whiplash
  • Neck pain
  • Post-surgical pain
  • Complex regional pain syndrome (CRPS),
  • Spinal pain
  • Low back pain
  • Industrial injuries
  • Clinical negligence

Publications

Saxena N, Shaw A, Muthukumaraswamy S, Wise R, Singh KD: Robust resting-state oscillatory fingerprints of GABA-ergic and non-GABA-ergic sedation, BIOMAG 2022. Birmingham, U.K., 2022, pp 454

Chiarelli AM, Germuska M, Chandler H, Stickland R, Patitucci E, Biondetti E, Mascali D, Saxena N, Khot S, Steventon J, Foster C, Rodriguez-Soto AE, Englund E, Murphy K, Tomassini V, Wehrli FW, Wise RG: A flow-diffusion model of oxygen transport for quantitative mapping of cerebral metabolic rate of oxygen (CMRO2) with single gas calibrated fMRI. J Cereb Blood Flow Metab 2022; 42: 1192-1209

Chandler HL, Stickland RC, Patitucci E, Germuska M, Chiarelli AM, Foster C, Bhome-Dhaliwal S, Lancaster TM, Saxena N, Khot S, Tomassini V, Wise RG: Reduced brain oxygen metabolism in patients with multiple sclerosis: Evidence from dual-calibrated functional MRI. J Cereb Blood Flow Metab 2022: 271678X221121849

Chiarelli AM, Germuska M, Chandler H, Stickland R, Patitucci E, Biondetti E, Mascali D, Saxena N, Khot S, Steventon J, Foster C, Rodriguez-Soto AE, Englund E, Murphy K, Tomassini V, Wehrli FW, Wise RG: Oxygen Transport Modelling for Mapping Brain Oxygen Extraction Fraction with Single Gas Calibrated fMRI, Joint Annual Meeting ISMRM-ESMRMB & ISMRT 31st Annual Meeting. London, 2022

Saxena N, Muthukumaraswamy SD, Richmond L, Babic A, Singh KD, Hall JE, Wise RG, Shaw AD: A comparison of GABA-ergic (propofol) and non-GABA-ergic (dexmedetomidine) sedation on visual and motor cortical oscillations, using magnetoencephalography. Neuroimage 2021; 245: 118659

Saxena N, Gili T, Diukova A, Huckle D, Hall JE, Wise RG: Mild Propofol Sedation Reduces Frontal Lobe and Thalamic Cerebral Blood Flow: An Arterial Spin Labeling Study, Proceedings of the International School on Magnetic Resonance and Brain Function – XIII Workshop. Edited by Ronen I, Bianciardi M, Giove F, Frontiers Media SA, 2021

Shaw AD, Muthukumaraswamy SD, Saxena N, Sumner RL, Adams NE, Moran RJ, Singh KD: Generative modelling of the thalamo-cortical circuit mechanisms underlying the neurophysiological effects of ketamine. Neuroimage 2020; 221: 117189

Rossiter H, Chandler H, Saxena N, Wise RG, Singh KD, Khot S. Oscillatory dynamics in ischaemic pain. British Journal of Pain 2020: 2

El-Mekki J, Saxena N. A service evaluation of the use of cannabidiol products among people with chronic/persistent pain, attending Cwm Taf Morgannwg University Hospitals. British Journal of Pain 2020: 1-2

Varanasi M, Saxena N. Patient engagement with a pre-clinic questionnaire in outpatient pain clinics. British Journal of Pain 2020: 3

Saxena N, Gili T, Diukova A, Huckle D, Hall JE, Wise RG: Mild Propofol Sedation Reduces Frontal Lobe and Thalamic Cerebral Blood Flow: An Arterial Spin Labeling Study. Frontiers in Physiology 2019; 10

Patitucci E, Stickland R, Chandler H, Germuska M, Foster C, Khot S, Saxena N, Tomassini V, Wise RG: Voxel-wise CMRO2 mapping reveals focally-reduced task-related oxygen consumption in multiple sclerosis., OHBM. Rome, 2019

Patitucci E, Foster C, Stickland R, Chandler H, Germuska M, Khot S, Saxena N, Tomassini V, Wise RG: Energetics of brain plasticity in the healthy and MS brain: a quantitative fMRI study OHBM. Rome, 2019

Chandler HL, Stickland R, Germuska M, Patitucci E, Foster C, Khot S, Saxena N, Bhome-Dhaliwal S, Tomassini V, Wise RG: Quantification of cerebral grey matter vascular and metabolic function in multiple sclerosis using dual-calibrated fMRI., ISMRM. Paris, 2019

 

Bosanquet D, Ambler G, Waldron CA, Thomas-Jones E, Brookes-Howell L, Kelson M, Pickles T, Harris D, Milosevic S, Fitzsimmons D, Saxena N, Twine C: Perineural local anaesthetic catheter after major lower limb amputation trial (PLACEMENT): results from a randomised controlled feasibility trial. BMJ Open 2019; 9: e029233

Bosanquet DC, Ambler GK, Waldron CA, Thomas-Jones E, Brookes-Howell L, Kelson M, Harris D, Pickles T, Milosevic S, Fitzsimmons D, Saxena N, Twine CP: Major lower limb amputation audit – introduction and implementation of a multimodal perioperative pain management guideline. Br J Pain 2018; 12: 257-258

Stickland R, Germuska M, Chandler H, Foster C, Saxena N, Khot S, Tomassini V, Wise RG: Visual stimulus induced changes in oxygen metabolism in Multiple Sclerosis, School of Brain Cells and Circuits: From cell physiology to integrated signals and emerging brain functions, 2017

Saxena N: Investigating the role of GABA in sedation: A combined neurophysiological, haemodynamic and spectroscopic study in humans School of Medicine, Cardiff University, 2017

Bosanquet DC, Ambler GK, Waldron CA, Thomas-Jones E, Brookes-Howell L, Kelson M, Pickles T, Harris D, Fitzsimmons D, Saxena N, Twine CP: Perineural local anaesthetic catheter after major lower limb amputation trial (PLACEMENT): study protocol for a randomised controlled pilot study. Trials 2017; 18: 629

Saxena N, Gili T, Huckle D, Bell S, Hall J, Wise R: Mild propofol sedation reduces frontal lobe and thalamic cerebral blood flow: an arterial spin labelling study. British Journal of Anaesthesia 2016; 117: e841

Saxena N, Forsyth A, Babic A, Dasari S, Richmond L, Worthen S, Hall J, Muthukumaraswamy S: Dissociating analgesic and sedative actions of anaesthetic drugs with magnetoencephalography (MEG); Initial results., 16th World Congress on Pain. Yokohama, Japan, IASP, 2016, pp PTH392

Saxena N, Babic A, Richmond L, Shaw A, Hall J, Muthukumaraswamy S: Visual stimulus-induced oscillatory activity can differentiate between GABAergic and non-GABAergic sedation. British Journal of Anaesthesia 2016; 11: e841- e842

Shaw AD, Saxena N, L EJ, Hall JE, Singh KD, Muthukumaraswamy SD: Ketamine amplifies induced gamma frequency oscillations in the human cerebral cortex. Eur Neuropsychopharmacol 2015; 25: 1136-46

Richmond L, Jackson L, Shaw A, Hall J, Saxena N, Muthukumaraswamy S: The neural, oscillatory, correlates of sedative ketamine infusion: a pharmaco-MEG (magnetoencephalographic) study. European Journal of Anaesthesiology 2015; 32: 183

Muthukumaraswamy SD, Shaw AD, Jackson LE, Hall J, Moran R, Saxena N: Evidence that Subanesthetic Doses of Ketamine Cause Sustained Disruptions of NMDA and AMPA-Mediated Frontoparietal Connectivity in Humans. J Neurosci 2015; 35: 11694-706

Warnert EA, Harris AD, Murphy K, Saxena N, Tailor N, Jenkins NS, Hall JE, Wise RG: In vivo assessment of human brainstem cerebrovascular function: a multi-inversion time pulsed arterial spin labelling study. J Cereb Blood Flow Metab 2014; 34: 956-63

Muthukumaraswamy S, Jackson LE, Saxena N, Shaw A, Wise R, Hall JE: Investigating glutamatergic neuro-transmission in the human brain using ketamine sedation. British Journal of Anaesthesia 2014; 113: 328-329P

Clark J, Short A, Chawathe M, Francis J, Saxena N, Bogod D, Girotra V: Development of a realistic epidural simulator – a translational research project. Anaesthesia 2014; 69: 17

Saxena N, Muthukumaraswamy SD, Diukova A, Singh K, Hall J, Wise R: Enhanced Stimulus-Induced Gamma Activity in Humans during Propofol-Induced Sedation. PLoS One 2013; 8: e57685

Saxena N: Airway management plan in patients with difficult airways having regional anesthesia. J Anaesthesiol Clin Pharmacol 2013; 29: 558-60

Harris AD, Murphy K, Diaz CM, Saxena N, Hall JE, Liu TT, Wise RG: Cerebral blood flow response to acute hypoxic hypoxia. NMR Biomed 2013

Gili T, Saxena N, Diukova A, Murphy K, Hall JE, Wise RG: The thalamus and brainstem act as key hubs in alterations of human brain network connectivity induced by mild propofol sedation. J Neurosci 2013; 33: 4024-31

Saxena N, Muthukumaraswamy S, Diukova A, Wilkes A, Singh KD, Wise RG, Hall JE: Alterations of stimulus-induced gamma oscillatory activity during propofol sedation. Anaesthetic Reasearch Society. London, British Journal of Anaesthesia, 2012, pp 870P – 871P

Saxena N, Kumar M, Tailor N, Wilkes T, Hodzovic I: Comparing performance of three non-rebreathing Oxygen masks – Topout, Intersurgical™ and Flexicare™. A randomised, cross-over volunteer study. British Journal of Anaesthesia 2012; 109: 665-666P

Saxena N, Kadambande S, Khot S: From presentation to journal publication: the journey of our Society’s ASM abstracts. Pain News 2012; 10: 49-52

Saxena N, Jeffs S, Hughes O: Do Pain Management Programmes lead to permanent changes? Long-term effectiveness of an outpatient interdisciplinary PMP: an observational study. World Congress on Pain. Milan, IASP, 2012

Saxena N, Diukova A, Venzi M, Gili T, Huckle D, Bell S, Wise RG, Hall JE: Endogenous brain oscillations during sedation: initial results of a magnetoencephalography and functional magnetic resonance imaging study. British Journal of Anaesthesia 2012; 108: 721P

Kumar M, Saxena N, Wilkes T, Hodzovic I: Evaluation of three non-rebreathing Oxygen delivery masks. British Journal of Anaesthesia 2012; 109: 660P

Khurana A, Guha A, Saxena N, Pugh S, Ahuja S: Comparison of aprotinin and tranexamic acid in adult scoliosis correction surgery. Eur Spine J 2012

Harris AD, Roberton VH, Huckle DL, Saxena N, Evans CJ, Murphy K, Hall JE, Bailey DM, Mitsis G, Edden RA, Wise RG: Temporal dynamics of lactate concentration in the human brain during acute inspiratory hypoxia. J Magn Reson Imaging 2012

Gili T, Saxena N, Diukova A, Murphy K, Hall J, Wise R: Mild sedation alters eigenvector centrality of BOLD FMRI in the thalamus and brainstem OHBM Proceedings 2012

Gili T, Saxena N, Diukova A, Murphy K, Hall J, Wise R: Physiological noise correction may help to detect changes in brain activity during mild sedation. . OHBM Proceedings 2012

Gili T, Saxena N, Diukova A, Murphy K, Hall J, Wise R: Mapping alterations in cortical and subcortical functional connectivity induced by light sedation. . OHBM Proceedings 2012

Saxena N: Do Pain Management Programmes lead to permanent changes? Long term effectiveness of an outpatient interdisciplinary Pain Management Programme. An observational study, School of Medicine, Cardiff University, 2011

Saxena N, Lewis E: Anaesthetic interventions for vaginal twin deliveries; role of epidural analgesia. International Journal of Obstetric Anaesthesia 2010: S42

Edden RA, Harris AD, Murphy K, Evans CJ, Saxena N, Hall JE, Bailey DM, Wise RG: Edited MRS is sensitive to changes in lactate concentration during inspiratory hypoxia. J Magn Reson Imaging 2010; 32: 320-5

Saxena N, Parry-Jones AJ: Traumatic haemorrhage into an occult phaeochromocytoma: presentation and management in a patient with septic shock. Anaesthesia 2008; 63: 428-32

Saxena N, Greenway I, Harding LJ, Davies NG: A complication of the ‘atraumatic inserter’ of the Tracoe experc percutaneous dilation tracheostomy set. Anaesthesia 2008; 63: 1377-9

Kumar M, Saxena N, Saxena A: The effect of a colloid or crystalloid preload on hypotension caused by induction of anaesthesia with propofol and fentanyl. Journal of Anaesthesiology Clinical Pharmacology 2008; 24: 409-412

Khot S, Taylor A, Saxena N, Knox G: Chronic low back pain: What doctors think?, British Pain Society- Annual Scientific Meeting, British Pain Society, 2007

Saxena N, Sharma M: Cerebral infarction following carotid arterial injection of adrenaline. Can J Anaesth 2005; 52: 119

Saxena N, Chaudhary S: Open indirect cardiac massage in a neonate. Indian J Pediatr 2005; 72: 253-5

Saxena AK, Saxena N, Aggarwal B, Sethi AK: An unusual complication of sinus arrest following right-sided stellate ganglion block: a case report. Pain Pract 2004; 4: 245-8

Saxena N, Ahuja S: Laryngeal mask cuff damage during interscalene block. Anaesthesia 2003; 58: 600

Saxena N, Sharma M, Mishra KK, Kumar A: Comparative evaluation of the effect of glycopyrrolate with thiopentone or propofol, for modified ECT on cardiovascular parameters and seizure characteristics., ISA-GOLDCON. Coimbatore, 2002

Saxena N: To study the effect of fluid preloading on propofol and fentanyl induced haemodynamic changes during induction of anaesthesia. Anaesthesiology, Critical Care and Pain Medicine, Delhi University, 2002

Non- academic

Saxena N: Meet our new Trainee Representative, Transmitter; Newsletter of the Faculty of Pain Medicine, 2010, pp 6

Saxena N: Update from the Trainee Representative, Transmitter: Newsletter of the Faculty of Pain Medicine, 2011, pp 7

Saxena N: Trainee Update, Transmitter: Newsletter of the Faculty of Pain Medicine, 2011, pp 6

Saxena N: Trainee update, Transmitter: Newsletter of the Faculty of Pain Medicine, 2012, pp 9

Availability

Prof. Saxena has weekly availability in clinic venues in Cardiff. He is also available for home visits

 

Languages spoken

  • English – Fluent
  • Punjabi – Fluent
  • Urdu – Fluent
  • Hindi – Fluent

Qualifications and memberships

Qualifications

MBBS, MD, MSc (Pain management), PhD (Neurosciences), DipILBM, DipMSK Medicine, FRCA, FFPMRCA

Professional memberships

BMA, British Pain Society, International Association on the study of Pain, Welsh Pain Society, MDDUS)

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